Biography
Biography: Marcela Rizzotto
Abstract
DNA is a dynamic molecule that is constantly damaged and repaired. Major sources of DNA lesions are physical and chemical agents from the environment, intermediates of cellular metabolism, spontaneous chemical reactions of DNA, incorporation of foreign or damaged nucleotides, etc. Mutagens are not only involved in genotoxicity and carcinogenesis but also involved in the pathogenesis of several chronic degenerative diseases including hepatic disordes, diabetes, ageing process and so on. One of the best ways to minimize the detrimental effects of mutagens is by the use of natural antimutagens. These include flavonoids, coumarins, carotenoids, tannins and many more.
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