Toxicology

Biography

Leon F. Stankowski, Jr., PhD, received BS degrees from The Pennsylvania State University in pre-medicine and biophysics; studied toward a MS in biochemistry at the University of Scranton; and received a PhD in biomedical sciences, specializing in genetics, from the University of Tennessee – Oak Ridge Graduate School of Biomedical Sciences. Since then, he has held various scientific and management positions in contract research organizations and the pharmaceutical industry. He has served a study director for a variety of in vitro and in vivo genetic toxicology assays, and as a program manager or consultant. This latter involves advising clients who have encountered adverse genetic toxicology findings, including the design of custom protocols and mechanistic studies to resolve them. Dr. Stankowski has directed thousands of assays in multiple in vivo and in vitro test systems; has had a lead role in developing and validating novel mutagenesis, in vitro toxicity and biochemistry methods and services; and has published original research results in multiple journals and presented at numerous meetings. He is a member of the Environmental Mutagenesis and Genomics Society and the Genetic Toxicology Association (GTA), and served on the GTA Board of Directors from 2000 to 2003, as the GTA Assistant Treasurer from 2003 to 2006, and as the GTA Treasurer from 2006 to present. He has been a reviewer for several journals in the field, served on numerous industrial workgroups involving in vitro and in vivo mammalian mutagenesis assays, including ASTM, IWGT, US EPA, and ILSI-HESI, and is a US Delegate to the Expert Working Group for the review of most of the OECD Test Guidelines on Genotoxicity.

Abstract

Abstract : Genotoxicity. Basic aspects and most commonly worldwide employed and validated in vitro assays