16^th Global Summit on Toxicology and Applied Pharmacology October 15-16, 2018 Las Vegas, Nevada, USA

Christophor Dlshovsky was born in Sofia, Bulgaria, in 1940. He graduated in 1966 from Sofia Medical University. From 1968 to 1971 he was PhD student in All-Union Institute of Hygiene and Toxicology in Kiev, Ukraine (former USSR) and obtained a PhD degree in Kiev Medical Institute (1971). D.Sc. degrees in toxicology he obtained in Military Medical Academy, Sofia (1989). Professor of Toxicology (1989) and Pharmacology (1996), with extensive experience of almost 45 years in Toxicology, Pharmacology. Included in the Golden Book of Bulgarian Discoverers and Inventors. ERT from 2012. President of the Bulgarian Commission for ERT. Honored President of Bulgarian Toxicological Society (member of EUROTOX and IUTOX). Member of Nomination Committee of EUROTOX (2008-2011), he was nominated for President of IUTOX in 2010. Member of Bulgarian Medical Academy and Academician of Bulgarian Academy of Science and Art.

Toxicology and pharmacology of drugs; investigation of new antidotes of intoxications; new biological markers for nerve agent exposure and antidote treatment of intoxications; esterase status for diagnostics and prognosis of OPC intoxications

Shao-yu Chen, Ph.D., is a tenured Professor and University Scholar at the Department of Pharmacology and Toxicology in the University of Louisville. Dr. Chen received his Ph.D. degree in 1991 in China and was trained as a postdoctoral associate in the University of North Carolina at Chapel Hill. Dr. Chen joined the University of Louisville in 2014. Dr. Chen has conducted alcohol-related birth defects research for more than 20 years. His research program, funded by multiple NIH R01 grants, focuses on elucidation of cellular and molecular mechanisms of Fetal Alcohol Spectrum Disorders. Dr. Chen has published a number of papers in high profile journals, including PNAS, Nat Commun, and EMBO J. Dr. Chen has been serving as an editorial board member of the Oxidative Medicine and Cellular Longevity and other journals. Dr. Chen has also served as a grant reviewer for NIH and other international agencies.

Elucidation of cellular and molecular mechanisms of alcohol-induced birth defects utilizing a combination of experimental approaches including interference, technology, and ultrasound-guided in utero microinjection in cellular, whole embryo and in vivo mouse models.

Dr. Karen G.Mulkijanyan currently holds positions of Head of the Department of Preclinical Pharmacological Research at Tbilisi State Medical University (TSMU) I.Kutateladze Institute of Pharmacochemistry and full Professor at the Caucasus International University Faculty of Medicine He obtained MS in Biochemistry in 1981, and PhD in Pharmacy in 2005. Dr. Mulkijanyan was a manager/ key investigator of research projects funded by CRDF Global/GRDF, STCU, GNSF/SRSNF. As Organizing Committee Member, he arranged several international congresses and conferences on pharmacology and pharmacy. Dr. K.Mulkijanyan co-authored more than 100 scientific publications, 30 presentations at international scientific meetings and 2 patents in pharmacology. Dr. K.Mulkijanyan is Founder and President of the Georgian Association for Laboratory Animal Science, a member of the Association of Professional Chemists of Georgia and Association of University Technology Managers.

Pharmacology of anti-inflammatory, ulcer preventive, burn and wound healing drugs; analysis of structure-activity relationship (SAR) and prediction of bioactivity of natural, modified and synthesized compounds; intellectual property protection; technology transfer and technology commercialization, use and care of laboratory animals.

Jonathan Freedman is a Professor in the Department of Pharmacology and Toxicology at the University of Louisville School of Medicine. He received his Ph.D. in 1986 Molecular Pharmacology at the Albert Einstein College of Medicine

His research program focuses on understanding the mechanisms by which transition metals affect the transcription of both specific genes and entire genomes through the activation of intracellular signal transduction pathways ultimately leading to adverse human health effects. A second research area is to develop in vivo toxicological assays using the nematode Caenorhabditis elegans and evaluate their utility as medium- and high-throughput screening tools. This research area is part of the international effort to reduce, refine or replace vertebrate animals in chemical testing.

Mustafa I. Selim is a Professor in the Department of Pharmacology and Toxicology at the Brody School of Medicine at East Carolina University, USA

Research in Dr. Selim's laboratory is focused on two areas: 1) investigating the toxic and detoxification mechanisms of hazardous and cancer causing chemicals, such as pesticides and mycotoxins (particularly aflatoxin B1), with the goal of developing technology for treatment or mitigation of exposure to such chemicals.2) method development and application of modern analytical techniques (e.g. SFE, GC/MS & LC/MS) for studying: the effect of air pollutants on cardiovascular and upper respiratory diseases; assessing the health effects of human exposure to toxic and endocrine disrupting chemicals in drinking water, foods, dietary supplements, and consumer products.