Pharmacology and Toxicology

Pharmacokinetic and pharmacodynamics

Pharmacokinetics is the study of drug absorption, distribution, metabolism, and excretion A fundamental concept in pharmacokinetics is drug clearance, that is, elimination of drugs from the body, analogous to the concept of creatinine clearance. Pharmacodynamics studies about a drug's molecular, biochemical, and physiologic results and acts. All drugs at the molecular level produce their effects by interacting with biological structures or targets to induce a change in how the target molecule functions with respect to following intermolecular interactions

• Pharmacokinetic aspects
• Drug biotransformation reactions
• Drug interactions and pharmacological compatibilities
• Clinical efficacy and safety evaluation
• Receptor theory for drug effects