Pharmacokinetic and pharmacodynamics

Pharmacokinetics is the study of drug absorption, distribution, metabolism, and excretion A fundamental concept in pharmacokinetics is drug clearance, that is, elimination of drugs from the body, analogous to the concept of creatinine clearance. Pharmacodynamics studies about a drug's molecular, biochemical, and physiologic results and acts. All drugs at the molecular level produce their effects by interacting with biological structures or targets to induce a change in how the target molecule functions with respect to following intermolecular interactions

  • Pharmacokinetic aspects
  • Drug biotransformation reactions
  • Drug interactions and pharmacological compatibilities
  • Clinical efficacy and safety evaluation
  • Receptor theory for drug effects


 

 

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