Pharmacology and Toxicology

Toxicologic Pathology

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Toxicological pathology integrates the disciplines of toxicology and pathology. In the early days of toxicological pathology, pathologists often worked independently. Their evaluations of chemical-induced changes were limited to morphologic observations made at necropsy and during microscopic examination of tissue sections. As toxicological pathology data became a major component of risk assessment, toxicological pathologists needed a knowledge base beyond understanding morphologic changes in tissues. Toxicological pathology continues to evolve and the skills of the toxicological pathologist are keeping pace with this evolution. The result is high-quality and timely data that contributes to more informed decisions for clinical programs and regulations and ultimately leads to improvement of human, animal, and environmental health.